Lecture/Discussion

Molecular Neurodegeneration and Therapeutic Approaches

25–29 July 2022

Wellcome Genome Campus, UK

Summary

This popular course will provide an overview of the molecular basis of neurodegenerative disorders, and is aimed at individuals working in neurodegenerative research, neurogenetics or translational neuroscience.

The programme will cover several neurological disorders, including Huntington’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and various forms of dementia, including Alzheimer’s disease. Discussions will also highlight therapeutic approaches for combating neurodegeneration, bioinformatics techniques used in neurogenetics and experimental models for neurodegenerative disease.

Returning to the Wellcome Genome Campus, the programme will include popular aspects of our successful 2021 virtual event.  This year’s combined format will comprise of a mixture of in-person and live-streamed lectures, live Q&A sessions, participant presentations and plenty of face-to-face networking opportunities with other attendees and experts in the field.

The course will benefit researchers who seek a comprehensive view of both neurodegenerative disorders and state of the art research techniques.  It further aims to give a deeper insight into participants own research.

We encourage applications from PhD students, clinical scientists, veterinary scientists, post-doctoral researchers and researchers based in the pharmaceutical and biotechnology industries.

Learning outcomes

Following attendance of this course, participants will be able to:

  1. Describe and recognize the heterogeneity in clinical symptoms and pathological hallmarks of the major neurodegenerative diseases.
  2. Explain the mechanisms of disease pathogenesis in Parkinson’s disease, Huntington’s disease, Amyotrophic lateral sclerosis and others.
  3. Learn and evaluate the different disease models used to study this range of disorders.
  4. Learn and evaluate the current therapeutic opportunities available and in development for this range of disorders.
  5. Discuss the generation of patient-derived induced pluripotent stem cells (iPSCs) and its use in deciphering mechanisms of disease in neurodegenerative diseases, both sporadic and familial.
  6. Identify and understand the value of applying various genomic approaches.
  7. Explain the general principles of experimental models of various neurodegenerative disease.

Programme

This residential course will run from 11:00 on Monday, 25 July and will close at approximately 14:00 Friday, 29 July 2022.

Topics will include:

  • Parkinson’s Disease
  • Huntington’s Disease
  • Amyotrophic lateral sclerosis
  • Dementia and amyloids
  • Tau dementia
  • Clinical and pathological aspects of neurodegeneration
  • Development of therapeutic approaches
  • Genetic analysis in neurodegenerative disease
  • Molecular and human stem cell models of neurodegeneration.

Instructors and speakers

Scientific Programme Committee

Nancy Bonini
University of Pennsylvania, USA

Karen Duff
University College London, UK

Rita Sattler
Barrow Neurological Institute, USA

Patrik Verstreken
VIB-KU Leuven Center for Brain and Disease Research, Belgium

Confirmed Instructors

A full list of speakers and instructors will be released shortly

Organisers – Wellcome Connecting Science

Lucy Criddle – Course Organiser
Jane Murphy – Scientific Programme Officer

How to apply

Application and bursary deadline is Tuesday 17 May, 2022.

How to apply for the course

Places on this course are limited and will be awarded on merit. Applicants should be currently engaged in relevant research and will be required to complete an online application form.
Be prepared to provide:

  • Qualifications and justification for attendance
  • A list of relevant publications
  • An outline of current research
  • details of a scientific or clinical referee (e.g. supervisor, line manager or head of department).

Referees will automatically be sent a request for a supporting statement as part of the application process.
Please ensure your referee sends in a statement before the deadline for your application to be considered.

If you have any problems with the online application process, please contact the course organiser.

Travel visas

Citizens of many countries can travel to the UK for a course without needing a visa.
Please check the UK government website for visitor information
https://www.gov.uk/standard-visitor.

Confirmed attendees requiring a letter to support a visa application should contact the course organiser.

 

Cost

Cost Accommodation / meals
Course fee* £860 This is a residential course and the fee includes all accommodation and meals.

*The course fee is subsidised by Wellcome Connecting Science Courses and applies to non-commercial applicants.
Please contact us for the commercial fee.

The fee will be requested once acceptance is confirmed.

Extra accommodation
If you wish to book onsite accommodation either side of the course dates, please contact the Conference Centre directly.

Please be vigilant for accommodation services phishing scams. More information on accommodation scams is available.

Bursaries

A limited number of bursaries (up to 50% of the fee) are available from Wellcome Connecting Science.
Priority for bursaries will be given to PhD students and those from under-resourced regions.

To apply for a bursary, please send the course organiser the following supporting documents:

  • a letter stating financial need and explaining how you will benefit from attending the course
  • a statement from your supervisor explaining financial need
  • CV

All required documents and a completed online application form must have been submitted before the deadline for your bursary application to be considered.

If you have any questions, please contact the course organiser.

We will be in contact with the result of your application shortly after the deadline.

Testimonials

Feedback from students on our last two Molecular Neurodegeneration courses:

“I really enjoyed the course and the balance of mechanistic understanding of the different diseases, models to study them and the therapeutic opportunities. I also really enjoyed the poster presentations”

“The course instructors were excellent speakers and their approachability made the course really insightful as everyone had time and the freedom to ask questions.”

“It was an excellent opportunity to interact with the academic community and discuss relevant topics in our area of research, establish contacts and gain insights to strengthen not only our PhD projects but also our labs”

“Very satisfied with the course itself and its organization, will definitely recommend it to my colleagues and look for more courses at Welcome Genome Campus in the future”

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