Devising a Consensus Framework for Validation of Novel Human Coding Loci

11–13 May 2015

Wellcome Genome Campus, UK


The chromosome-centric Human Proteome Project (c-HPP) is a large multidisciplinary international effort to catalogue human gene products, focusing on so-called ‘missing proteins’, those which have little evidence at the protein level. Aprox 18 % of the human proteome lacks evidence at the protein level. This retreat brought together experts from the fields of genomics, transcriptomics, proteomics, and representatives from the major human genome and protein databases, to establish guidelines to validate human protein products. In addition set of standard guidelines were developed that the biocuration and scientific community can use to determine the evidence required to a novel coding loci being added or removed from the reference human gene sets (UniProt, GENCODE and RefSeq).

Scientific committee

Scientific programme committee

Jen Harrow
Wellcome Sanger Institute, UK

Elspeth Bruford
European Bioinformatics Institute, UK

Amos Bairoch
NeXtProt, Switzerland

Lydie Lane
NeXtProt, Switzerland

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