Developing Clinical Biomarkers for Mitochondrial Disease for Therapeutic Trials

April 27th - 28th 2015

Wellcome Genome Campus, UK

Summary

Recent advances in understanding the mechanisms of mitochondrial diseases have led to the development of new treatment approaches that show real promise in animal models. The field has also come together to assemble genetically defined cohorts of patients, ready for interventional studies. However, there are a limited number of clinically-relevant biomarkers available to assess disease progression before or during treatment. The aim of this retreat was to bring together experts to help break down the biomarker ‘road-block’ and lead to well-informed treatment trials.

Scientific committee

Scientific programme committee

Patrick Chinnery
University of Newcastle, UK

Jan Smeitink
Nijmegen, The Netherlands

Mike Murphy
University of Cambridge, UK

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